Cardinal Health — Aug 12, 2025 release

Cardinal Health Page 3 Fiscal year 2026 outlook 2 The company raised its fiscal year 2026 outlook for non-GAAP diluted EPS to $9.30 to $9.50 (+13% to +15% growth), a $0.20 increase from the preliminary outlook of $9.10 to $9.30 previously communicated during the company’s 2025 Investor Day. Non-GAAP earnings per share $9.30 to $9.50 Pharmaceutical and Specialty Solutions segment: Revenue 11% to 13% growth Segment profit 11% to 13% growth Global Medical Products and Distribution segment: Revenue 2% to 4% growth Segment profit At least $140 million Other (NPHS, at-Home Solutions, OptiFreight Logistics): Revenue 26% to 28% growth Segment profit 25% to 27% growth Interest and other ~$275 million Non-GAAP effective tax rate 22.0% - 24.0% Diluted weighted average shares outstanding 238 million to 240 million Share repurchases ~$750 million Capital Expenditures ~$600 million Non-GAAP adjusted free cash flow $2.75 billion to $3.25 billion Bold indicates a change to the preliminary FY26 outlook provided in the Investor Day press release on June 12, 2025. The increase to non-GAAP diluted EPS reflects a benefit to net earnings of classifying the shares held by physicians and management of The Specialty Alliance as a liability as opposed to non-controlling interests within equity and increased contributions from the Pharmaceutical and Specialty Solutions segment and the growth businesses reported in Other. 3 Recent highlights • Cardinal Health hosted an Investor Day on June 12th, 2025 where management detailed the company's momentum, growth strategies and updated long-term value creation plans • Cardinal Health announced that the company entered into a definitive agreement to acquire Solaris Health