Quest Diagnostics — Oct 21, 2025 release

Updated Guidance for Full Year 2025 The company updates its full year 2025 guidance as follows: Updated Guidance Prior Guidance Low High Low High Net revenues $10.96 billion $11.00 billion $10.80 billion $10.92 billion Net revenues increase 11.0% 11.4% 9.4% 10.6% Reported diluted EPS $8.58 $8.66 $8.60 $8.80 Adjusted diluted EPS $9.76 $9.84 $9.63 $9.83 Cash provided by operations Approximately $1.8 billion Approximately $1.55 billion Capital expenditures   Approximately $500 million Approximately $500 million Note on Non-GAAP Financial Measures As used in this press release the term “reported” refers to measures under accounting principles generally accepted in the United States (“GAAP”). The term “adjusted” refers to non-GAAP operating performance measures that exclude special items such as restructuring and integration charges, amortization expense, excess tax benefits ("ETB") associated with stock-based compensation, gains and losses associated with changes in the carrying value of our strategic investments, impairment charges and other items. Non-GAAP adjusted measures are presented because management believes those measures are useful adjuncts to GAAP results. Non-GAAP adjusted measures should not be considered as an alternative to the corresponding measures determined under GAAP. Management may use these non-GAAP measures to evaluate our performance period over period and relative to competitors, to analyze the underlying trends in our business, to establish operational budgets and forecasts and for incentive compensation purposes. We believe that these non-GAAP measures are useful to investors and analysts to evaluate our performance period over period