Hologic — Jul 30, 2025 release

    Current Guidance     Previous Guidance       Guidance $   Reported % Increase (Decrease) Constant Currency % Increase (Decrease) Organic % Increase (Decrease) Organic excluding COVID-19 % Increase (Decrease)     Guidance $   Fiscal 2025                       Revenue   $4,081 - $4,091   1.3% to 1.5% 1.1% to 1.4% (0.5%) to (0.2%) 0.6% to 0.8%     $ 4,050 - $4,100   GAAP EPS   $2.56 - $2.59   (22.9%) to (22.0%)             $ 2.47 - $2.57   Non-GAAP EPS   $4.23 - $4.26   3.7% to 4.4%             $ 4.15 - $4.25                             Q4 2025                         Revenue   $1,030 - $1,040   4.3% to 5.3% 3.7% to 4.7% 2.7% to 3.7% 3.9% to 5.0%           GAAP EPS   $0.90 - $0.93   18.4% to 22.4%                 Non-GAAP EPS   $1.09 - $1.12   7.9% to 10.9%                 3 Use of Non-GAAP Financial Measures The Company has presented the following non-GAAP financial measures in this press release: constant currency revenues; organic revenues; organic revenues excluding COVID-19; non-GAAP gross margin; non-GAAP operating expenses; non-GAAP operating margin; non-GAAP effective tax rate; non-GAAP net income; non-GAAP net income margin; non-GAAP EPS; adjusted EBITDA; adjusted net leverage ratio and adjusted ROIC. Organic revenue for the fiscal third quarter of 2025 excludes the divested Blood Screening and SSI ultrasound imaging businesses and the acquired Endomagnetics and Gynesonic