Incyte — Feb 10, 2025 release

Guidance for other oncology net product revenues include net product revenue for Monjuvi in follicular lymphoma and Zynyz in squamous cell anal carcinoma. Approvals for these indications are anticipated in the second half of 2025. Current Jakafi net product revenues $2,925 - $2,975 million Opzelura net product revenues $630 - $670 million Other oncology net product revenues (1) $415 - $455 million GAAP Cost of product revenues 8.5% - 9.0% of net product revenues Non-GAAP Cost of product revenues (2) 7.5% - 8.0% of net product revenues GAAP Research and development expenses $1,930 - $1,960 million Non-GAAP Research and development expenses (3) $1,780 - $1,805 million GAAP Selling, general and administrative expenses $1,280 - $1,310 million Non-GAAP Selling, general and administrative expenses (3) $1,160 - $1,185 million 1 Pemazyre in the U.S., EU and Japan; Niktimvo, Monjuvi and Zynyz in the U.S.; and Iclusig and Minjuvi in the EU. 2 Adjusted to exclude the amortization of licensed intellectual property for Iclusig relating to the acquisition of the European business of ARIAD Pharmaceuticals, Inc. and the estimated cost of stock-based compensation. 3 Adjusted to exclude the estimated cost of stock-based compensation. Conference Call and Webcast Information Incyte will hold a conference call and webcast this morning at 8:00 a.m. ET. To access the conference call, please dial 877-407-3042 for domestic callers or 201-389-0864 for international callers. When prompted, pr